Cellular Ingestible DNA Nanostructures for Biomedical Applications
نویسندگان
چکیده
Delivering functional substances across the cell membrane barriers has been a great challenge in biomedicine. Among various strategies to improve cellular uptake, DNA nanostructures, with different shapes and sizes, supply as suitable platforms for delivering wide range of cells. With programmability, biocompatibility, biostability, nanostructure-based delivery systems have shown succeeded anticancer therapy, antibacterial treatment, gene editing, vaccine development, stem bioengineering. Herein, development construction ingestible nanostructures are described, loading summarized, current biomedical applications overviewed, finally remaining challenges opportunities discussed.
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ژورنال
عنوان ژورنال: Advanced nanoBiomed research
سال: 2022
ISSN: ['2699-9307']
DOI: https://doi.org/10.1002/anbr.202200119